Fig. 4: Differentiation trajectory and functional state of CD8 and CD4 T cells by treatment and tissue type.
From: The dynamic immune behavior of primary and metastatic ovarian carcinoma

Differentiation trajectory analysis of A CD8 T cells and B CD4 T cells projecting the expression of multiple cell types representing different stages of differentiation. Inference of T cell functionality based on gene expression modules for C T cell cytotoxicity, D T cell dysfunction, and E T-reg scores, showing clustering by tissue type and treatment.