Table 1 Summary of breast cancer patient recruitment and BC-hiPSC generation

From: Examining patient-specific responses to PARP inhibitors in a novel, human induced pluripotent stem cell-based model of breast cancer

Breast cancer patient ID

ER/PR/HER2 status

BRCA status

# BC-hiPSC lines

BC1

ER/PR +

 

2

BC2

ER +

 

122

BC3

ER/PR +

 

16

BC4

ER/PR +

 

10

BC5

ER/PR +

 

21

BC6

ER/PR +

BRCA2 p.V1283fs*

13

BC7

ER/PR/HER2 +

 

10

BC8

Triple-negative

BRCA1 p.E23fs*

3

BC9a

Triple-negative

 

1

BC9b

N/A (fibroadenoma)

 

15

  1. BRCA status includes known variants in BRCA1 and BRCA2 identified through clinical gene sequencing panels. BC9a and BC9b tissues were obtained from the same patient with contralateral breast cancer. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2.
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