Fig. 1: Expression level of piR-28846 and its effect on ovarian cancer cells and its therapeutic effect.
From: piRNA28846 has the potential to be a novel RNA nucleic acid drug for ovarian cancer
aThe expression levels of piR-28846 in ovarian cancer tissue specimens (n = 108) and normal ovarial tissue specimens (n = 29) was detected by q-PCR. b The effect of piR-28846 expression on cellular growth was detected by CCK-8 assay. c Community aggregation experiments showed that overexpression of piR-28846 inhibited the formation of ovarian cancer cell communities. d piR-28846 overexpression promoted apoptosis. e CAOV3 was inoculated into nude mice, and the growth rate of the tumor was significantly slowed down after agopiR-28846 treatment compared with control group. f The volume and weight of the xenograft tumor.
