Fig. 3: Cell type composition across all samples.
From: The single-cell spatial landscape of stage III colorectal cancers
a The box plots showing the distribution of all cell type proportions, b immune cell type proportions across all samples (n = 52), c stacked bar plot illustrating cell type proportions in MSI (n = 9) and MSS (n = 33) samples, ordered by CD8 + T cell proportion, d representative IMC images of tissue region from a patient with the highest CD8 + T cell proportion, e a patient with the lowest CD8 + T cell proportion, f box plots comparing the proportion of p53+ tumor cells and CD8 + T cells between MSI and MSS tumors (*p < 0.05), g cell type proportion correlation correlograms for patients with tumor recurrence (MSI: n = 5, MSS: n = 26), showing only significant correlations (Spearman’s correlation, adjusted p ≤ 0.05). Color scale bar indicates the strength and direction of correlations across tissue regions.
