Table 2 Differences in APC mutation types between our study and the study by Aretz et al
From: Uncovering the genetic variation spectrum of colorectal polyposis from a multicentre cohort in China
APC mutation number | Point mutation N (%) | Large fragment deletion N (%) | Other | ||||
|---|---|---|---|---|---|---|---|
Frameshift mutation | Nonsense mutation | Splice mutation | Missense mutation | ||||
Aretz et al. (2005) | 634 | 364 (57.4%) | 182 (28.7%) | 38 (6.0%) | 13 (2.1%) | 37 (5.8%) | 0 |
Our study | 85 | 39 (45.9%) | 35 (41.2%) | 1 (1.1%) | 0 | 8 (9.4%) | 2 (2.4%) |
P value | 0.0443 | 0.0187 | 0.0656 | 0.1828 | 0.2012 | 0.0001 | |
