Fig. 5: Effects of SNVs and CNVs of 25 cancer driver genes on TIL score distributions.

A Effects of SNV on TIL score distributions. TIL scores were compared in SNV and non-SNV patient groups. B Effects of CNV (copy deletion) on TIL score distributions. TIL scores were compared in the deletion and non-deletion patient groups. C Effects of CNV (copy amplification) on TIL score distributions. TIL scores were compared in the amplification and non-amplification patient groups. Color-filled squares indicate significant differences in TIL score distributions for two groups (SNV and non-SNV, CNV and non-CNV) (t-test). Gray squares indicate the number of SNV and CNV cases for a gene in a cancer type is 0. Filled numbers represent the patient numbers and proportions of CNV or SNV for each gene in each cancer type. “*”, P < 0.05; “**”, P < 0.01; “***”, P < 0.001.