Fig. 4: Association of nine TLS-associated signature gene sets with prognosis and immunotherapy efficacy in AM patients.

A Kaplan-Meier curve analysis of the relationship between TLS-associated signature gene sets and OS. B Kaplan-Meier curve analysis of the relationship between TLS-associated signature gene sets and DFS. C Differences in TLS-associated signature gene scores between the response and non-response groups to immunotherapy. TLS tertiary lymphoid structures, AM acral melanoma, OS overall survival, DFS disease-free survival.