Fig. 5: Filanesib and luminespib induce G2/M cell cycle arrest in HB cells. | npj Precision Oncology

Fig. 5: Filanesib and luminespib induce G2/M cell cycle arrest in HB cells.

From: Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma

Fig. 5: Filanesib and luminespib induce G2/M cell cycle arrest in HB cells.

Representative histograms of flow cytometry analysis after 10 nM filanesib treatment of HB-279 cells (A) HB-284 cells (B) and HB-243 (C) for 24 h. Representative histograms of flow cytometry analysis after 50 nM luminespib treatment of HB-279 cells (D) HB-284 cells (E), and HB-243 cells (F) for 48 h. Bar plots show the percentage of cells in each phase of the cell cycle of four independent experiments presented as mean ± SD. ** p < 0.01 (Student’s t-test).

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