Fig. 4: Knockout of IL18 inhibits proliferation, migration, and invasion of glioma cells.

The effects of IL18 knockout on colony formation in U118MG and U251MG cells (A) and histogram analysis (B). The results of wound healing assays after IL18 knockout in U118MG and U251MG cells (C) and histogram analysis (D). The effects of IL18 knockout on Transwell assays in U118MG and U251MG cells (E) and histogram analysis (F) (*p < 0.05, **p < 0.01, ***p < 0.001).