Fig. 1: Clinical and histological appearance of Merkel cell carcinoma in a case of spontaneous tumor regression and avelumab-driven regression.

A Tumor at baseline and during spontaneous regression at week 3 (left), with corresponding Hematoxylin and Eosin (H&E), Keratin 20 (CK20), and Chromogranin A (ChrA) staining at baseline (right). B Tumor at baseline and during avelumab-mediated regression at week 6 (left), with corresponding H&E, CK20, and ChrA staining at baseline (right). Original magnifications of micrographs 100x and 200x.