Table 1 Application of the RED algorithm to the spiked cell dataset

From: Unsupervised detection of rare events in liquid biopsy assays

 

TPR (\(\bar{N}=2,500\))

AUROC

Cell type

Mean

St. dev.

Min.

Max.

Mean

St. dev.

Min.

Max.

SK-BR-3

0.993

0.014

0.962

1.00

1.00

0.0

1.00

1.00

HPAEC

0.965

0.031

0.927

1.00

0.999

2.00 × 10−3

0.993

1.00

All

0.985

0.020

0.943

1.00

0.999

1.00 × 10−3

0.997

1.00

  1. Columns 2-5: statistics for the true positive rate for a cohort of 2500 rare tiles identified by the algorithm. Columns 6-9: statistics for the AUROC obtained by varying \(\bar{N}\) from 0 to N. Values are reported for CTCs (Row 1), endothelial cells (Row 2) and their combination (Row 3).
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