Fig. 3: Impact of loss function weighting on ROS1 trade-off plots.
From: Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach
A–D Trade-off plots for the ROS1 test sets using different positive weights in the loss function: 5 (A), 10 (B), 20 (C), and 30 (D). The x-axis represents the false negative rate (false negatives divided by the total number of cases), while the y-axis represents the true negative rate (true negatives divided by the total cases) for the red plot, and PPA for the blue plot. Increasing the positive weight shifts the blue plot toward the top-left (indicating improved PPA and reduced false negatives) and the red plot toward the bottom-left (indicating reduced false negatives at the expense of lower true negatives).
