Fig. 6: HMSC HPV signature is upregulated in HPV + OPSCC and is associated with poor prognosis. | npj Precision Oncology

Fig. 6: HMSC HPV signature is upregulated in HPV + OPSCC and is associated with poor prognosis.

From: Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

Fig. 6

A Violin plots show upregulation of HMSC HPV signature in HPVon relative to HPVoff cells (t-test, p < 0.05) for all ten individual OPSCC tumors (each p < 0.01). B Kaplan-Meier curves of TCGA all OPSCC (left) and HPV + OPSCC (right) patients stratified by expression of HMSC HPV signature. Red survival curves represent patients with high expression of HMSC HPV genes and demonstrate poorer survival in both analyses (p < 0.01).

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