Table 4 Significant correlations between the clinical/demographic variables and the rare events identified by HDSCA3.0 in the liquid biopsy samples collected from the PoVB and PB (Pre-procedure) from PDAC patients
Variable | Rare event | Clinical metric | Correlation method | Correlation value | P-Value |
|---|---|---|---|---|---|
PB | CK | V Onco | Age | Spearman | 0.3834 | 0.0191 |
PB | CK Onco | Gender | Wilcoxon Rank Sum | −2.4066 | 0.0161 |
PB | D | CD | Mass Location: body | Wilcoxon Rank Sum | −2.1594 | 0.0308 |
PB | D | V | CD | Survival Status | Wilcoxon Rank Sum | −3.2609 | 0.0011 |
PB | D | CK | V | CD | Survival Status | Wilcoxon Rank Sum | −2.3314 | 0.0197 |
PB | Total CK+ Cells | Survival Status | Wilcoxon Rank Sum | −2.3162 | 0.0205 |
PB | Total Cells | Survival Status | Wilcoxon Rank Sum | −2.2552 | 0.0241 |
PB | Total Events | Survival Status | Wilcoxon Rank Sum | −2.2552 | 0.0241 |
PB | D | V | CD | Survival Time from EUS | Spearman | −0.3866 | 0.0218 |
PB | CK | CD Onco | Survival Time from EUS | Spearman | −0.3717 | 0.0279 |
PB | D | CK | CD | Survival Time from EUS | Spearman | −0.3518 | 0.0382 |
PoVB | Mes.CTC | 1-year Survival | Wilcoxon Rank Sum | 2.6404 | 0.0083 |
PoVB | Total Oncosomes | Age | Spearman | −0.3771 | 0.0214 |
PoVB | Total Events | Age | Spearman | −0.3440 | 0.0371 |
PoVB | Total Cells | Age | Spearman | −0.3351 | 0.0426 |
PoVB | Total CK+ Cells | Age | Spearman | −0.3326 | 0.0443 |
PoVB | D | V | Location of Mass | Wilcoxon Rank Sum | 2.1213 | 0.0339 |
PoVB | D | CK | CD | Mass Location: head | Wilcoxon Rank Sum | 2.6819 | 0.0073 |
PoVB | D | CK | CD | Mass Location: Tail | Wilcoxon Rank Sum | −2.7390 | 0.0062 |
PoVB | D | Survival Time from EUS | Spearman | −0.4475 | 0.0070 |
PoVB | Mes.CTC | Survival Time from EUS | Spearman | −0.3628 | 0.0322 |
PoVB | D | V | Survival Time from EUS | Spearman | −0.3530 | 0.0375 |
