Table 1 Patient information
Responder | Non-responder | |
|---|---|---|
Age at diagnosis | 59 | 68 |
Race/Ethnicity | Non-Hispanic White | Non-Hispanic White |
Body mass index at cycle 1 | 24.4 | 32.9 |
ECOG performance status | 1 | 1 |
Prior lines of therapy | 6 | 10 |
Baseline metastatic status | Intraperitoneal only | Extraperitoneal and intraperitoneal |
PIPAC cycles received | 6 | 2 |
Baseline PCI | 20 | 20 |
Cycle 2 PCI | 19 | 14 |
Baseline mean PRGS | 3 | 3.5 |
Baseline ascites volume | 1500 mL | 10 mL |
Best response per RECIST | Partial response | Progressive disease |
PFS (months) | 21.6 | 1.7 |
OS (months from PIPAC initiation) | 33.6 | 11.9 |
OS months from initial diagnosis | 124.3 | 92.9 |
Off-treatment reason | Treatment completed per protocol | RECIST-based progression |
Progression type | Intraperitoneal | Extraperitoneal and liver parenchymal |
Grade | Low grade | Low grade |
Stage | 3 | 4 |
