Fig. 2: Characterization of the epithelial cells in SCC, ACC, and normal tissue samples. | npj Precision Oncology

Fig. 2: Characterization of the epithelial cells in SCC, ACC, and normal tissue samples.

From: A single-cell atlas reveals the tumorigenesis and microenvironment status of primary tracheobronchial tumors

Fig. 2: Characterization of the epithelial cells in SCC, ACC, and normal tissue samples.

A t-SNE plots of epithelial cells subgroups within SCC samples. B CopyKAT was used to discriminate tumor cells (in red) from normal epithelial cells (in blue) within SCC samples. C CytoTRACE results of all epithelial cells representing the degree of differentiation within SCC samples. D t-SNE plots of epithelial cells subgroups within ACC samples. E CopyKAT was used to discriminate tumor cells (in red) from normal epithelial cells (in blue) within ACC samples. F CytoTRACE results of all epithelial cells representing the degree of differentiation within ACC samples. G Immunofluorescence staining showing the expression of key markers BIRC5 and EPCAM in tumor and normal trachea tissues (scale bar, 50 μm). (Yellow arrows indicate representative cells positive for both EPCAM and BIRC5.) H RNA velocity analysis of the tumor cells and pseudotime expression trends of BIRC5 in SCC and ACC.

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