Table 4 Comparisons of CT findings between nodules with and without VPI in the internal and external test sets
From: Integrated predictive model for visceral pleural invasion in small NSCLC with high clinical utility
Pleural-attached nodules | Pleural-tag nodules | |||||||
|---|---|---|---|---|---|---|---|---|
Characteristics | VPI (24)a | non-VPI (136) | Total (160) | P value | VPI (23)a | non-VPI (171) | Total (194) | P value |
Nodule type | <0.001 | 0.004 | ||||||
PSN | 4 (16.67%) | 99 (72.79%) | 103 (64.38%) | 11 (47.83%) | 130 (76.02%) | 141 (72.68%) | ||
SN | 20 (83.33%) | 37 (27.21%) | 57 (35.63%) | 12 (52.17%) | 41 (23.98%) | 53 (27.32%) | ||
Mean diameter | 19.75±5.08 | 15.69±5.85 | 16.30±5.91 | 0.002 | 19.53±4.84 | 15.58±4.79 | 16.05±4.94 | <0.001 |
Nodule-pleura attachment distance (mm) | 16.93±8.91 | 12.19±7.24 | 12.90±7.67 | 0.014 | ||||
Nodule-pleura distance (mm) | 5.13±2.59 | 5.43±4.60 | 5.40±4.40 | 0.395 | ||||
Indentation | 0.893 | 0.036 | ||||||
positive | 19 (79.17%) | 106 (77.94%) | 125 (78.13%) | 22 (95.65%) | 131 (76.61%) | 153 (78.87%) | ||
negative | 5 (20.83%) | 30 (22.06%) | 35 (21.88%) | 1 (4.35%) | 40 (23.39%) | 41 (21.13%) | ||
Pleural tag type | 0.023 | |||||||
I | 0 | 42 (24.56%) | 42 (21.65%) | |||||
II | 17 (73.91%) | 102 (59.65%) | 119 (61.34%) | 0.581 | ||||
III | 6 (26.09%) | 27 (15.79%) | 33 (17.01%) | |||||
PIF | 0.51±0.13 | 0.29±0.22 | 0.32±0.22 | <0.001 | ||||
Jellyfish sign | 0.006 | |||||||
positive | 11 (45.83%) | 27 (19.85%) | 38 (23.75%) | |||||
negative | 13 (54.17%) | 109 (80.15%) | 122 (76.25%) | |||||
Bridge tag sign | 0.403 | |||||||
positive | 6 (26.09%) | 32 (18.71%) | 38 (19.59%) | |||||
negative | 17 (73.91%) | 139 (81.29%) | 156 (80.41%) | |||||
Involved pleural type | ||||||||
Interlobar pleura | 1 (4.17%) | 42 (30.88%) | 43 (26.88%) | 0 | 17 (9.94%) | 17 (9.76%) | ||
non-Interlobar pleura | 15 (62.50%) | 69 (50.74%) | 84 (52.50%) | 0.434 | 19 (82.61%) | 140 (81.87%) | 159 (81.96%) | 0.219 |
Complex pleura | 8 (33.33%) | 25 (18.38%) | 33 (20.63%) | 4 (17.39%) | 14 (8.19%) | 18 (9.28%) | ||
Solid component (PSN+SN) | 23 | 103 | 126 | 21 | 128 | 149 | ||
Mean diameter | 19.37±5.60 | 12.24±6.86 | 13.54±7.18 | <0.001 | 16.77±4.71 | 11.95±5.16 | 12.63±5.35 | <0.001 |
Solid component-pleura attachment distance (mm) | 16.65±9.10 | 9.73±7.14 | 11.00±7.96 | <0.001 | ||||
Solid component-pleura distance (mm) | 5.75±2.61 | 7.56±5.24 | 7.30±4.99 | 0.289 | ||||