Fig. 9: ACACA promoted tumor growth by alleviating the accumulation of R-loops and DNA damage in vivo. | npj Precision Oncology

Fig. 9: ACACA promoted tumor growth by alleviating the accumulation of R-loops and DNA damage in vivo.

From: ACACA modulates R-loop homeostasis to enhance lipid metabolism and microenvironmental interactions in ccRCC

Fig. 9: ACACA promoted tumor growth by alleviating the accumulation of R-loops and DNA damage in vivo.The alternative text for this image may have been generated using AI.

A Representative images of whole-body in vivo imaging once every five days after transplantation with Caki-1 transfected with sh-ACACA or sh-NC (n = 5), B HE staining for the tumor sample in the two groups (n = 5) (magnification: ×200, Bar = 100 μm), C IHC staining of Ki67 for the tumor sample in the two groups (n = 5) (magnification: ×200, Bar = 100 μm), D IF staining of S9.6 (n = 5) (magnification: ×200, Bar = 100 μm), E IF staining of γH2AX (n = 5) (magnification: ×200, Bar = 100 μm).

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