Table 1 Baseline characteristics of trial participants

From: Impact of predictive medicine on therapeutic decision making: a randomized controlled trial in congenital heart disease

 

Experimental group: Conventional & modelling data

Control group: Conventional data

p-value for difference

Case 1

n = 90

n = 88

 

Gender

34.5

35.8

0.86

Proportion female (95% CI)

(24.3–44.7)

(25.1–46.5)

 

Region

69.0

69.1

0.98

Proportion practicing in Western Europe (95% CI)

(59.0–78.9)

(58.9–79.4)

 

CHD experience

81.8

75.3

0.29

Proportion with >5 years of experience with decision making in CHD (95% CI)

(73.6–90.0)

(66.1–84.4)

 

CoA experience

85.2

80.7

0.43

Proportion with treatment experience on >5 CoA cases in the past year (95% CI)

(77.7–92.8)

(72.3–89.1)

 

Catheter intervention experience

38.6

29.5

0.21

Proportion with experience in performing catheter interventions on >5 cases per year (95% CI)

(28.3–49.0)

(19.8–39.3)

 

Case 2

n = 83

n = 89

 

Gender

36.3

34.1

0.77

Proportion female (95% CI)

(25.5–47.0)

(23.9–44.2)

 

Region

65.0

72.7

0.28

Proportion practicing in Western Europe (95% CI)

(54.3–75.7)

(63.2–82.2)

 

CHD experience

80.7

77.3

0.58

Proportion with >5 years of experience with decision making in CHD (95% CI)

(72.1–89.4)

(68.3–86.2)

 

CoA experience

78.3

86.2

0.18

Proportion with treatment experience on >5 CoA cases in past year (95% CI)

(69.3–87.4)

(78.8–93.6)

 

Catheter intervention experience

34.9

34.5

0.95

Proportion with experience in performing catheter interventions on >5 cases per year (95% CI)

(24.5–45.4)

(24.3–44.7)

 

Case 3

n = 92

n = 79

 

Gender

35.6

34.6

0.89

Proportion female (95% CI)

(25.5–45.6)

(23.8–45.4)

 

Region

71.1

66.7

0.54

Proportion practicing in Western Europe (95% CI)

(61.6–80.7)

(56.0–77.4)

 

CHD experience

71.4

87.3

0.01*

Proportion with >5 years of experience with decision making in CHD (95% CI)

(62.0–80.9)

(79.8–94.8)

 

CoA experience

76.7

88.8

0.04*

Proportion with treatment experience on >5 CoA cases in the past year (95% CI)

(67.8–85.6)

(81.4–95.8)

 

Catheter intervention experience

36.7

32.9

0.62

Proportion with experience in performing catheter interventions on >5 cases per year (95% CI)

(26.5–46.8)

(22.3–43.5)

 
  1. CHD congenital heart disease, CoA coarctation of the aorta, CI confidence interval
  2. *Statistically significant at 0.05 level