Table 1 Examples of organizations and industries that have undergone digital disruption or have successfully transformed themselves by implementing digital solutions.

From: Digital clinical trials: creating a vision for the future

Industry or organization

Core business

Transformational change

Digital disruption enhance existing income model?

Successful internal transformation?

Examples of digital disrupters

Photography supplies

Photographic film & paper

Digital photography

No

×

Sony

Book stores

In person selection & selling of books

Online book search & sales

No

×

Amazon

Financial institutions

In person money lending

ATMs and online banking

Yes

Video & DVD rental

In person selection & rental

Digital browsing and streaming

No

×

Netflix

Traditional clinical research organizations

In-person recruitment & management of study participants

Participant-centric digitally-enabled clinical trials

No

?

Apple ResearchKit

  1. The traditional clinical research enterprise should take action to benefit from digital disruption, rather than attempting to maintain the status quo, which has made numerous traditional entities obsolete