Table 2 Research opportunities and potential action Items from the NIH/NSF workshop on digital clinical trials.

Leveraging digital technologies to transform clinical trials

• Capitalize on existing technologies and research platforms

• Incorporate testing and the adoption of new approaches

• Leverage the science from which other areas of information technology have already benefited (e.g., Artificial Intelligence)

• Ensure trial technology tools are accessible for people with low digital and reading literacy

• Develop partnerships with new technology and computational communities

Incorporating technology to enhance clinical trials

• Develop standard protocol templates that include automation for recruitment, retention, and data collection

• Develop validation models for new devices and analyses using existing trials and tools

• Develop common standards for data collection and transmission and the use of standard data elements

• Create depositories of digital tools and methods

Committing to use of digital technology to address disparities

• Develop partnerships between technology developers, researchers and community advocates

• Make investments in the next generation workforce in medicine, technology, and clinical research

• Bring broadband and Wi-Fi access to rural communities