Table 1 Research contexts of studies that evaluated Artificial Intelligence implementations in low- and middle-income countries.

From: Artificial intelligence for strengthening healthcare systems in low- and middle-income countries: a systematic scoping review

Study

Study focus

Study design

Study outcome

Study methodology

Analytical approach

Study sample

Love et al.17

Training of non-radiologist healthcare workers in a Mexican hospital to use AI CADx system to triage palpable breast lumps for further examination by oncologists

Cross-sectional study

The concordance between AI’s scoring of breast lumps, when used by non-radiologist health workers, and a radiologist’s BI-RADS of the breast lumps

Quantitative

Predictive analysis

32 palpable breast lumps, examined by three non-radiologist health workers using AI tool

Zhou et al.20

The performance of IBM Watson for Oncology when producing treatment plans for cervical cancer patients in a Chinese university hospital

Cross-sectional study

Concordance between AI recommended and ‘for consideration’ treatments, and treatments implemented by physicians

Quantitative

Inferential analysis

362 retrospective cancer patients; single case-study patient

Kisling et al.21

The ability of MD Anderson’s ‘Radiation Planning Assistant’ to automate the production of safe and effective radiotherapy treatment plans for cervical cancer patients in two South African hospitals

Cross-sectional study

The acceptability and accuracy of AI generated treatment plans by specialists in gynaecologic radiation oncology, in addition to AI run-time for generating plans

Quantitative

Descriptive analysis

14 cervical cancer patients

Ugarte-Gil et al.15

The utility of the ‘eRx’ CADx system for TB diagnostics in primary care clinics in Peru, and the challenges of implementing such a system from the user’s perspective

Cross-sectional study

The experiences of nurses and doctors with the technology, including barriers and complications that arose

Mixed methods

Descriptive and content analysis of reported provider experiences

Seven nurses and five doctors working at primary care hospital or health centres

Garzon-Chavez et al.18

The implementation of an AI-assisted CT screening tool for COVID-19 patient triage in the workflows of an Ecuadorian hospital

Cross-sectional study

The sensitivity and specificity of AI-assisted CT screening to correctly identify likely COVID-19 positives as confirmed by RT-PCR test

Quantitative

Predictive analysis

75 chest CTs for patients with laboratory confirmed SARS-CoV-2 diagnosis

Fan et al.23

The real-world use of an AI health chatbot for primary care self-diagnosis in China, including issues and barriers in their usage, and user experiences

Cross-sectional study

The characteristics of users, length and frequency of chatbot sessions, health concerns presented, and user feedback

Mixed methods

Descriptive and inferential analysis of chatbot sessions; content analysis of user feedback

47,684 consultation sessions initiated by 16,519 users

Ganju et al.16

The use of an Indian child health and nutrition education mHealth app’s usage data to predict user churn and target interventions to improve user engagement

Cross-sectional study

The engagement and retention of users with mHealth app

Quantitative

Predictive analysis of user churn

45,000 mHealth app users

Wang et al.22

The experiences of physicians using a clinical decision support system for diagnostic assistance and treatment suggestions in rural primary care clinics in China

Cross-sectional study

The perspectives of physician using the AI tool, including the perceived challenges, limitations, trustworthiness, and usefulness of the tool

Qualitative

Content analysis

22 clinicians from rural primary care clinics

Wang et al.24

The anonymous implementation of a social support chatbot for online pregnancy healthcare in a community in China

Cross-sectional study

The AI’s response rate and response time to community members, and emotional valence of responses, compared with responses from other community members

Mixed methods

Descriptive analysis, content analysis

3445 users of YouBaoBao online pregnancy healthcare community

MacPherson et al.19

The improvement in patient outcomes and cost-effectiveness of implementing an X-ray CADx screening tool for TB in a primary clinic in Malawi, as part of an existing HIV-TB screening programme

Randomised controlled trial

The time in days, up to 56 days, to TB treatment initiation compared with standard-of-care and HIV treatment arm, and ICER of TB screening treatment arm

Quantitative

Economic analysis

1462 resident adults attending health centre reporting TB symptoms with no history of TB