Table 1 Sample sizes. Number of patients, person years and events for the three efficacy outcomes of the study across the three databases after excluding patients with prior outcomes.

From: A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases

 

Thiazides or thiazide-like diuretics

  

Ace inhibitors

  

Outcome

Patients

Person years

Outcomes

Patients

Person years

Outcomes

CCAE

Acute myocardial infarction

355,826

204,593

405

930,369

584,167

1813

Hospitalization with heart failure

355,528

204,451

389

930,629

584,541

1492

Stroke

354,446

203,792

425

923,604

579,736

1636

MDCD

Acute myocardial infarction

54,835

21,440

76

106,492

51,481

440

Hospitalization with heart failure

54,354

21,290

212

105,005

50,878

835

Stroke

54,259

21,179

149

104,410

50,334

562

MDCR

Acute myocardial infarction

37,882

24,642

161

105,852

74,990

732

Hospitalization with heart failure

37,617

24,509

277

105,134

74,654

1196

Stroke

37,248

24,267

261

102,502

72,705

977