Table 2 Summary of neurophysiological sensors used in the reviewed literature, including the anatomical location of recording sensor and the expected neurophysiological response to pain.

From: A systematic review of neurophysiological sensing for the assessment of acute pain

Sensor

Effect of pain

(↑) Increase, (↓) Decrease

Location of recording sensor

Studies

EDA

(↑) Skin conductance

(↓) Skin resistance

Palmar surface of index and ring fingers

28,34,35,36,37,38,39,40

Palmar surface of index and middle fingers

29,31,32,33,98,160

Palmar surface of two fingers

41

Abode and below second knuckle of hand

161

Wrist

42,43,44,45

sEMG

(↑) Trapezious muscle activity

Upper right trapezious

28,34,35,37

Corrugator supercilii

98

(↑) Corrugator supercilii muscle activity

Trapezious, corrugator supercilii, and zygomaticus

38,39,160

(↑) Zygomaticus major muscle activity

Cheek and corrugator supercilii

41

RESP

(↑) Inspiration

(↓) Breathing rate

Thorax

34,41,98

–

53,136

SpO2

(↑) Oxygen saturation

–

53,136

BP

(↑) Systolic BP

(↓) Diastolic BP

–

53

ECG

(↓) HRV

(↑) HR

Right and left wrist

46

Thorax

28,34,35,36,37,38,39,40,41,49,160

–

136

Wrist and ankle

33

MOVE

(↓) Movement

(↓) Steps

Wrist

43,44

SKT

(↓) Skin temperature

Wrist

43,44

–

53

Fingertip of non-dominant hand

33

PUPIL

(↓) Pupillary diameter

Eyes

56,136

PPG

(↑) HR or pulse rate

(↓) Blood volume pulse

(↓) Pulse transit time

Left index finger

40,49,52,117,161

Wrist

43,44,118

–

53

Left ring finger

98

Thumb of non-dominant hand

33

EEG

N2 and P2 activation

(↓) Alpha

(↓) Beta

(↑) Delta

(↑) Theta

(↑) Gamma

Full head

61,62,72,83,84,94,103,129,161

Head circumference

59,63,64,92,93

fNIRS

(↓) HbR

(↑) HbO

Somatosensory area

66,69,85,86

Prefrontal and somatosensory area

96

Prefrontal area

70,71