Fig. 2: Cosinor fit used to extract parametric measures from continuous actigraphy with minute-by-minute activity. | npj Digital Medicine

Fig. 2: Cosinor fit used to extract parametric measures from continuous actigraphy with minute-by-minute activity.

From: Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response

Fig. 2

Cosinor fit (red line) used to extract parametric measures over the 7 days of continuous actigraphy data (blue lines) from a sample participant with MDD. Each dot on the plot signifies one minute in time and the height of the line indicates motor activity for that minute. 1 day length of data (recorded from midnight to midnight) is indicated by the horizontal length of the purple rectangular box. Amplitude (brown double arrow) is indicated at half the distance between peaks of the fitted waveform. Acrophase (φ, dark olive, double arrow) refers to the time of the point of peak activity. MESOR (Midline Estimating Statistic of Rhythm, green dashed line) indicates the average cycle value.

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