Table 2 Univariate and multivariate linear mixed-effects models results.

From: Blood glucose variance measured by continuous glucose monitors across the menstrual cycle

 

Covariate

Univariate Model

Multivariate Model

β-coefficient [95% CI]

β-coefficient [95% CI]

Physiological signals

Menstrual phase

Late-follicular

Reference

Reference

Ovulation

0.06 [0.001, 0.12]*

0.08 [0.01, 0.15]*

Luteal

0.15 [0.09, 0.20]***

0.16 [0.10, 0.22]***

Menstrual

0.09 [0.02, 0.16]**

0.03 [-0.04, 0.11]

Others

Luteinizing Hormone (LH)

–0.001 [-0.01, 0.003]

Estrogen (E3G)

–0.0003 [–0.001, –0.00001]*

–0.0003 [–0.001, –0.0001]**

Step Count

–0.0003 [–0.0004, –0.0002]***

–0.0003 [–0.0004, –0.0002]***

Demographics

 

Age (yrs)

0.01 [–0.04, 0.05]

 

Height (cm)

–0.01 [–0.04, 0.02]

 

Weight (kg)

0.002 [–0.01, 0.02]

 

BMI (kg/m²)

0.01 [–0.03, 0.05]

Self-reported experiences

Daily appetite

Very low

Reference

Reference

Low

–0.02 [–0.13, 0.10]

Moderate

0.04 [–0.08, 0.15]

High

–0.01 [–0.13, 0.12]

Very high

–0.02 [–0.20, 0.15]

Daily exercise

Very low

Reference

Reference

Low

–0.02 [–0.08, 0.05]

Moderate

–0.02 [–0.09, 0.05]

High

–0.08 [–0.17, 0.02]

Very high

–0.05 [–0.24, 0.13]

Daily food cravings

Did not experience

Reference

Reference

Very low

0.05 [–0.05, 0.14]

0.05 [–0.05, 0.15]

Low

0.15 [0.07, 0.24]***

0.19 [0.10, 0.28]***

Moderate

0.19 [0.10, 0.28]***

0.21 [0.12, 0.30]***

High

0.15 [0.06, 0.24]**

0.17 [0.07, 0.27]***

Very high

0.08 [–0.05, 0.20]

0.04 [–0.09, 0.17]

Daily bloating

Did not experience

Reference

Reference

Very low

–0.06 [–0.15, 0.03]

Low

0.02 [–0.06, 0.11]

Moderate

0.04 [–0.05, 0.13]

High

0.07 [–0.03, 0.17]

Very high

–0.07 [–0.22, 0.08]

Daily fatigue

Did not experience

Reference

Reference

Very low

–0.14 [–0.26, −0.04]**

–0.16 [–0.28, –0.03]*

Low

0.03 [–0.07, 0.14]

0.02 [–0.09, 0.13]

Moderate

0.01 [–0.09, 0.10]

–0.03 [–0.13, 0.08]

High

0.03 [–0.07, 0.13]

–0.03 [–0.14, 0.08]

Very high

0.08 [–0.03, 0.20]

0.03 [–0.10, 0.16]

Daily sleep issues

Did not experience

Reference

Reference

Very low

0.001 [–0.10, 0.10]

0.05 [–0.06, 0.16]

Low

–0.04 [–0.13, 0.06]

–0.06 [–0.16, 0.05]

Moderate

0.04 [–0.06, 0.13]

0.02 [–0.09, 0.13]

High

0.11 [0.004, 0.22]*

0.05 [–0.07, 0.17]

Very high

0.09 [–0.03, 0.22]

0.02 [–0.12, 0.16]

  1. The results of the univariate and multivariate linear mixed-effects models that were generated to estimate changes in median blood glucose across menstrual phases. Significant model results are indicated as such *p < 0.05, **p < 0.01, ***p < 0.001.