Fig. 4: Proportions for times spent of motor states as assessed by observer diaries, participant diaries and wearable accelerometer-based digital Parkinson’s Motor Diary (adPMD) ratings.
Distribution of daily Off times (a), On times (e) and Dyskinetic times (i) based on the simultaneous, half-hourly performed clinical diary/adPMD ratings from 63 participants from 2 consecutive days (8 am to 6 pm). Boxplots are shown with a central mark at the median, bottom, and top edges of the boxes at 25th and 75th percentiles, respectively, whiskers out to the most extreme points within 1.5 times the interquartile range, and outliers scoring more than 1.5 × IQR but at most 3 × IQR outside the quartiles. Displayed P values are from from Friedman tests with post-hoc Wilcoxon signed-rank tests with Bonferroni correction for multiple comparisons. Correlation analyses of daily Off times displaying exemplarily the scatter plot of calibrated adPMD and observer Off times and the corresponding Bland-Altman plot (b, c) and the corellation matrix (d). Correlation analyses of daily On times displaying exemplarily the scatter plot of calibrated adPMD and observer On times and the corresponding Bland-Altman plot (f, g) and the correlation matrix (h). j–l Correlation analyses of daily Dyskinetic times displaying exemplarily the scatter plot of calibrated adPMD and observer Dyskinetic times and the corresponding Bland-Altman plot (b, c) and the correlation matrix (d). Solid lines in scatter plots represent the regression line with 95%CI (dotted lines) and the gray area in (c, g, k) the limit of argreement (mean ± 1.96 SD). Numbers in right corner of scatter plots represent Pearson correlation coefficients and P values. In correlation matrices, * represent P < 0.05, ** P < 0.01 and *** P < 0.001 from Pearson’s correlation tests.
