Table 4 Comparison of POPS against methods found in our literature review of preoperative prediction of postoperative pain.

From: Development and prospective validation of postoperative pain prediction from preoperative EHR data using attention-based set embeddings

Study

Retrospective cohort size

Prospective cohort size

Patient interaction

Distribution of surgical services

Outcome

Performance

POPS (ours)

243,274

365

No

Orthopedic: 24.3%

General: 15.0%

Urology: 10.5%

Gynecology: 9.5%

Thoracic: 7.5%

Neurosurg.: 7.1%

Surg. Oncology: 5.9%

Other: 20.3%

Moderate and severe pain on postop days 0–4

0.72–0.79 AUC

Armstrong et al. 2023

17,079

 

Yes

General: 62.0%

Urology: 15.6%

Thoracic: 7.5%

Orthopedic: 5.5%

Neurosurg.: 3.1%

Gynecology: 1.7%

Vascular: 0.7%

Other: 3.9%

Severe pain on first postop day

0.66 optimism-corrected c-statistic

Van Driel et al. 2022

344

150

Yes

Orthopedic: 45.3%

General: 20.9%

Vascular: 19.5%

Other: 14.2%

Persistent post-surgical pain at 3 months

0.7 AUC

Rehberg et al. 2017

 

198

Yes

Surg. Oncology: 100%, only breast cancer surgeries

Max pain on first postop day

0.82 AUC

Hur et al. 2021

112,989

 

No

Unreported, 13 common procedures

30-day refill, new persistent use

0.66–0.68 AUC

Janseen et al. 2008

549

1035

Yes

Unreported, non-cardiac surgery

Severe pain 1 h after surgery

0.65 AUC

Kallman et al. 2003

 

1416

Yes

Unreported, non-cardiac surgery

Severe pain 1 h after surgery

0.73 AUC

Sommer et al. 2010

 

1490

No

Unreported, non-cardiac surgery

Mean pain (VAS) > 4

0.74–0.78 AUC

  1. AUC Area under the receiver operating curve.