Fig. 6: Wearable sensor-based objective gait biomarkers of Parkinson’s disease (PD).

The recommended objective gait features for early diagnosis, subtype differentiation, and disease monitoring are listed in this figure. TD tremor-dominant, PIGD postural instability and gait disorder, MAS more affected side, LAS less affected side, RoM range of motion, SiSt sit to stand, StSi stand to sit.1 Gait features for early detection of both TD and PIGD (for subtype-specific early detection details, please see Fig. 3 and Supplementary Table 1);2a Gait features for disease monitoring in TD subtype;2b Gait features for disease monitoring in PIGD subtype; 3Gait features for subtypes differentiation.