Fig. 2: Flow chart of the study. | npj Digital Medicine

Fig. 2: Flow chart of the study.

From: Clinical usefulness of digital twin guided virtual amiodarone test in patients with atrial fibrillation ablation

Fig. 2

We included a total of 115 patients and performed pacing at different AMD concentration settings. We observed changes in electrophysiological parameters and induced AF to assess virtual rhythm outcomes. AF termination at least once at any therapeutic dose was classified as Effective, while ongoing AF or AT was classified as Ineffective. Based on the results of virtual outcomes, we compared the clinical rhythm outcomes one year after clinical AMD usage. AAD antiarrhythmic drug, AF atrial fibrillation, AFCA atrial fibrillation catheter ablation, AMD amiodarone, APD90 90% of action potential duration, AT atrial tachycardia, DF dominant frequency, Smax the maximal restitution slope of action potential duration.

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