Table 1 Diagnostic performance of LLMs in four rounds
Model | Average number of diagnoses (SDa) | Coverage rate (%, 95% CIa) | Accuracy (%, 95% CIa) | Krippendorff’s Alpha |
|---|---|---|---|---|
GPT-3.5t | 4.4(1.0) | 22.8 (18.1–28.2) | 6.0 (3.7–9.5) | 0.643 |
Round 1 | 4.6(1.1) | 25.4 (15.9–37.5) | 4.5 (1.2–12.7) | |
Round 2 | 4.4(1.1) | 19.4 (11.2–31.0) | 7.5 (2.9–16.7) | |
Round 3 | 4.4(0.9) | 17.9 (10.0–29.3) | 3.0 (0.6–10.5) | |
Round 4 | 4.2(1.0) | 28.4 (18.4–40.7) | 9.0 (3.8–18.6) | |
GPT-4o | 5.3(1.0) | 64.2 (58.2–69.8) | 42.9 (37.0–49.0) | 0.664 |
Round 1 | 5.4(1.0) | 56.7 (44.1–68.6) | 35.8 (24.8–48.4) | |
Round 2 | 5.4(1.0) | 62.7 (50.1–73.9) | 43.3 (31.4–55.9) | |
Round 3 | 5.3(0.9) | 68.7 (56.2–79.1) | 47.8 (35.6–60.2) | |
Round 4 | 5.2(0.9) | 68.7 (56.2–79.1) | 44.8 (32.8–57.3) | |
Gemini-1.0-pro | 5.3(1.3) | 30.6 (25.3–36.4) | 16.4 (12.4–21.4) | 0.555 |
Round 1 | 5.3(1.5) | 31.3 (20.9–43.8) | 17.9 (10.0–29.3) | |
Round 2 | 5.4(1.3) | 32.8 (22.2–45.4) | 19.4 (11.2–31.0) | |
Round 3 | 5.3(1.3) | 26.9 (17.1–39.1) | 11.9 (5.7–22.3) | |
Round 4 | 5.2(1.2) | 31.3 (20.9–43.8) | 16.4 (8.9–27.6) | |
Gemini-1.5-pro | 5.2(0.9) | 53.4 (47.3–59.3) | 24.6 (19.8–30.2) | 0.720 |
Round 1 | 5.2(0.8) | 53.7 (41.3–65.8) | 22.4 (13.5–34.3) | |
Round 2 | 5.2(0.8) | 53.7 (41.3–65.8) | 28.4 (18.4–40.7) | |
Round 3 | 5.3(0.8) | 52.2 (39.8–64.4) | 23.9 (14.7–35.9) | |
Round 4 | 5.1(0.9) | 53.7 (41.3–65.8) | 23.9 (14.7–35.9) | |
Claude-2.1 | 4.6(0.8) | 40.3 (34.5–46.4) | 22.4 (17.7–27.8) | 0.656 |
Round 1 | 4.6(0.9) | 38.8 (27.4–51.4) | 20.9 (12.3–32.6) | |
Round 2 | 4.6(0.8) | 41.8 (30.1–54.4) | 23.9 (14.7–35.9) | |
Round 3 | 4.5(0.8) | 43.3 (31.4–55.9) | 22.4 (13.5–34.3) | |
Round 4 | 4.5(0.7) | 37.3 (26.1–49.9) | 22.4 (13.5–34.3) | |
Claude 3 Opus | 4.8(0.6) | 66.4 (60.5–71.9) | 44.4 (38.5–50.5) | 0.697 |
Round 1 | 4.8(0.7) | 64.2 (51.6–75.2) | 47.8 (35.6–60.2) | |
Round 2 | 4.8(0.6) | 68.7 (56.2–79.1) | 41.8 (30.1–54.4) | |
Round 3 | 4.9(0.6) | 65.7 (53.1–76.5) | 44.8 (32.8–57.3) | |
Round 4 | 4.8(0.5) | 67.2 (54.6–77.8) | 43.3 (31.4–55.9) | |
Claude 3.5 Sonnet | 5.6(0.7) | 76.1 (70.6–80.9) | 48.9 (42.9–54.9) | 0.780 |
Round 1 | 5.5(0.6) | 77.6 (65.7–86.5) | 47.8 (35.6–60.2) | |
Round 2 | 5.6(0.7) | 77.6 (65.7–86.5) | 49.3 (37.0–61.6) | |
Round 3 | 5.7(0.7) | 77.6 (65.7–86.5) | 52.2 (39.8–64.4) | |
Round 4 | 5.7(0.7) | 71.6 (59.3–81.6) | 46.3 (34.2–58.7) |