Fig. 5: Comparison of AUCROC between the EHR-based emulation and the ET integrated with drug-target prediction. | npj Digital Medicine

Fig. 5: Comparison of AUCROC between the EHR-based emulation and the ET integrated with drug-target prediction.

From: Advancing efficacy prediction for electronic health records based emulated trials in repurposing heart failure therapies

Fig. 5

a displays the comparison for each prognostic outcome measure, with a focus on the best-performing HF cohort, where the EHR-based emulation is highlighted in red, and the ET integrated with drug-target prediction is highlighted in blue. b shows the comparison based on (i) outcome measures and (ii) HF cohorts, respectively. As shown in (b), a significant improvement was observed in the ET integrated with drug-target prediction. Note: * indicates statistically significant improvement tested with a paired one-tailed t-test, where * represents P-value < 0.05, ** for P-value < 0.01, *** for P-value < 0.001, and **** for P-value < 0.0001.

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