Fig. 3: Demonstrates the application of SpAgents in the diagnosis of axSpA.
From: Early diagnosis of axial spondyloarthritis in primary care using multi-agent systems

This figure illustrates the diagnostic evidence from SpAgents for clinical cases. Case 1 (True Positive): A 29-year-old male with persistent back pain for over a year, where SpAgents successfully identified axSpA through integrated clinical symptoms, laboratory findings, and imaging evidence. Case 2 (False Negative): A 39-year-old male with back pain indicative of inflammatory back pain, but with inactive sacroiliac joint inflammation post-treatment; SpAgents determined that the criteria for axSpA were not met. RUI right upper ilium, RLI right lower ilium, RUS right upper sacrum, RLS right lower sacrum, LUI left upper ilium, LLI left lower ilium, LUS left upper sacrum, LLS left lower sacrum, SPARCC Spondyloarthritis Research Consortium of Canada, axSpA Axial Spondyloarthritis, CRP C-reactive Protein, ESR Erythrocyte Sedimentation Rate, HLA-B27 Human Leukocyte Antigen-B27.