Abstract
Microscopic pressure sensors that can rapidly detect small pressure variations are of value in robotic technologies, human–machine interfaces, artificial intelligence and health monitoring devices. However, both capacitive and transistor-based pressure sensors have limitations in terms of sensitivity, response speed, stability and power consumption. Here we show that highly sensitive pressure sensors can be created by integrating a conductive microstructured air-gap gate with two-dimensional semiconductor transistors. The air-gap gate can be used to create capacitor-based sensors that have tunable sensitivity and pressure-sensing range, exhibiting an average sensitivity of 44 kPa−1 in the 0–5 kPa regime and a peak sensitivity up to 770 kPa−1. Furthermore, by employing the air-gap gate as a pressure-sensitive gate for two-dimensional semiconductor transistors, the pressure sensitivity of the device can be amplified to ~103–107 kPa−1 at an optimized pressure regime of ~1.5 kPa. Our sensors also offer fast response speeds, low power consumption, low minimum pressure detection limits and excellent stability. We illustrate their capabilities by using them to perform static pressure mapping, real-time human pulse wave measurements, sound wave detection and remote pressure monitoring.
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The data that support the plots within this paper and other findings of this study are available from the corresponding authors upon reasonable request.
References
Jung, S. et al. Reverse-micelle-induced porous pressure-sensitive rubber for wearable human–machine interfaces. Adv. Mater. 26, 4825–4830 (2014).
Kang, D. et al. Ultrasensitive mechanical crack-based sensor inspired by the spider sensory system. Nature 516, 222–226 (2014).
Kim, D.-H. et al. Epidermal electronics. Science 333, 838–843 (2011).
Lipomi, D. J. et al. Skin-like pressure and strain sensors based on transparent elastic films of carbon nanotubes. Nat. Nanotechnol. 6, 788–792 (2011).
Tee, B. C.-K. et al. A skin-inspired organic digital mechanoreceptor. Science 350, 313–316 (2015).
Yeom, C. et al. Large-area compliant tactile sensors using printed carbon nanotube active-matrix backplanes. Adv. Mater. 27, 1561–1566 (2015).
Schwartz, G. et al. Flexible polymer transistors with high pressure sensitivity for application in electronic skin and health monitoring. Nat. Commun. 4, 1859 (2013).
Zang, Y. et al. Flexible suspended gate organic thin-film transistors for ultra-sensitive pressure detection. Nat. Commun. 6, 6269 (2015).
Mannsfeld, S. C. et al. Highly sensitive flexible pressure sensors with microstructured rubber dielectric layers. Nat. Mater. 9, 859–864 (2010).
Lee, S. et al. A transparent bending-insensitive pressure sensor. Nat. Nanotechnol. 11, 472–478 (2016).
Graz, I. et al. Flexible ferroelectret field-effect transistor for large-area sensor skins and microphones. Appl. Phys. Lett. 89, 073501 (2006).
Dellon, E. S., Mourey, R. & Dellon, A. L. Human pressure perception values for constant and moving one-and two-point discrimination. Plast. Reconstr. Surg. 90, 112–117 (1992).
Kaltenbrunner, M. et al. An ultra-lightweight design for imperceptible plastic electronics. Nature 499, 458–463 (2013).
Pan, L. et al. An ultra-sensitive resistive pressure sensor based on hollow-sphere microstructure induced elasticity in conducting polymer film. Nat. Commun. 5, 3002 (2014).
Pang, C. et al. A flexible and highly sensitive strain-gauge sensor using reversible interlocking of nanofibres. Nat. Mater. 11, 795–801 (2012).
Chae, S. H. et al. Transferred wrinkled Al2O3 for highly stretchable and transparent graphene–carbon nanotube transistors. Nat. Mater. 12, 403–409 (2013).
Metzger, C. et al. Flexible-foam-based capacitive sensor arrays for object detection at low cost. Appl. Phys. Lett. 92, 013506 (2008).
Lee, J. et al. Conductive fiber-based ultrasensitive textile pressure sensor for wearable electronics. Adv. Mater. 27, 2433–2439 (2015).
Lee, H.-K., Chang, S.-I. & Yoon, E. A flexible polymer tactile sensor: fabrication and modular expandability for large area deployment. J. Microelectromech. Syst. 15, 1681–1686 (2006).
Sekitani, T. et al. Organic nonvolatile memory transistors for flexible sensor arrays. Science 326, 1516–1519 (2009).
Takei, K. et al. Nanowire active-matrix circuitry for low-voltage macroscale artificial skin. Nat. Mater. 9, 821–826 (2010).
Lee, B.-Y., Kim, J., Kim, H., Kim, C. & Lee, S.-D. Low-cost flexible pressure sensor based on dielectric elastomer film with micro-pores. Sens. Actuators A Phys. 240, 103–109 (2016).
Lei, K. F., Lee, K.-F. & Lee, M.-Y. A flexible PDMS capacitive tactile sensor with adjustable measurement range for plantar pressure measurement. Microsyst. Technol. 20, 1351–1358 (2014).
Zhang, B. et al. Dual functional transparent film for proximity and pressure sensing. Nano Res. 7, 1488–1496 (2014).
Park, S. et al. Stretchable energy-harvesting tactile electronic skin capable of differentiating multiple mechanical stimuli modes. Adv. Mater. 26, 7324–7332 (2014).
Boutry, C. M. et al. A sensitive and biodegradable pressure sensor array for cardiovascular monitoring. Adv. Mater. 27, 6954–6961 (2015).
Pang, C. et al. Highly skin-conformal microhairy sensor for pulse signal amplification. Adv. Mater. 27, 634–640 (2015).
Tee, B. C. K. et al. Tunable flexible pressure sensors using microstructured elastomer geometries for intuitive electronics. Adv. Funct. Mater. 24, 5427–5434 (2014).
Pannemann, C., Diekmann, T. & Hilleringmann, U. Degradation of organic field-effect transistors made of pentacene. J. Mater. Res. 19, 1999–2002 (2004).
Sirringhaus, H. Reliability of organic field-effect transistors. Adv. Mater. 21, 3859–3873 (2009).
Manunza, I. & Bonfiglio, A. Pressure sensing using a completely flexible organic transistor. Biosens. Bioelectron. 22, 2775–2779 (2007).
Wang, Z., Volinsky, A. A. & Gallant, N. D. Crosslinking effect on polydimethylsiloxane elastic modulus measured by custom-built compression instrument. J. Appl. Polym. Sci. 131, 41050 (2014).
Chuang, H.-J. et al. High mobility WSe2 p-and n-type field-effect transistors contacted by highly doped graphene for low-resistance contacts. Nano Lett. 14, 3594–3601 (2014).
Zhao, W. et al. Evolution of electronic structure in atomically thin sheets of WS2 and WSe2. ACS Nano 7, 791–797 (2012).
Bertolazzi, S., Brivio, J. & Kis, A. Stretching and breaking of ultrathin MoS2. ACS Nano 5, 9703–9709 (2011).
Radisavljevic, B., Radenovic, A., Brivio, J., Giacometti, V. & Kis, A. Single-layer MoS2 transistors. Nat. Nanotechnol. 6, 147–150 (2011).
Kim, S. et al. High-mobility and low-power thin-film transistors based on multilayer MoS2 crystals. Nat. Commun. 3, 1011 (2012).
Zhao, M. et al. Large-scale chemical assembly of atomically thin transistors and circuits. Nat. Nanotechnol 11, 954–959 (2016).
Cheng, R. et al. Few-layer molybdenum disulfide transistors and circuits for high-speed flexible electronics. Nat. Commun. 5, 5143 (2014).
Noguchi, Y., Sekitani, T. & Someya, T. Organic-transistor-based flexible pressure sensors using ink-jet-printed electrodes and gate dielectric layers. Appl. Phys. Lett. 89, 3507 (2006).
Takahashi, T., Takei, K., Gillies, A. G., Fearing, R. S. & Javey, A. Carbon nanotube active-matrix backplanes for conformal electronics and sensors. Nano Lett. 11, 5408–5413 (2011).
Nichols, W. W. Clinical measurement of arterial stiffness obtained from noninvasive pressure waveforms. Am. J. Hypertens. 18, 3S–10S (2005).
Millasseau, S., Kelly, R., Ritter, J. & Chowienczyk, P. Determination of age-related increases in large artery stiffness by digital pulse contour analysis. Clin. Sci. 103, 371–377 (2002).
Munir, S. et al. Exercise reduces arterial pressure augmentation through vasodilation of muscular arteries in humans. Am. J. Physiol. Heart Circ. Physiol. 294, H1645–H1650 (2008).
Saunders, F. A., Hill, W. A. & Franklin, B. A wearable tactile sensory aid for profoundly deaf children. J. Med. Syst. 5, 265–270 (1981).
Yang, J. et al. Eardrum-inspired active sensors for self-powered cardiovascular system characterization and throat-attached anti-interference voice recognition. Adv. Mater. 27, 1316–1326 (2015).
Kang, K. et al. High-mobility three-atom-thick semiconducting films with wafer-scale homogeneity. Nature 520, 656–630 (2015).
Yu, H. et al. Wafer-scale growth and transfer of highly-oriented monolayer MoS2 continuous films. ACS Nano 11, 12001–12007 (2017).
Xu, H. et al. High-performance wafer-scale MoS2 transistors toward practical application. Small 14, 1803465 (2018).
Lin, Z. et al. Solution-processable 2D semiconductors for high-performance large-area electronics. Nature 562, 254–258 (2018).
Lacour, S. P., Wagner, S., Huang, Z. & Suo, Z. Stretchable gold conductors on elastomeric substrates. Appl. Phys. Lett. 82, 2404–2406 (2003).
Lacour, S. P., Jones, J., Wagner, S., Li, T. & Suo, Z. Stretchable interconnects for elastic electronic surfaces. Proc. IEEE 93, 1459–1467 (2005).
Graz, I. M., Cotton, D. P. & Lacour, S. P. Extended cyclic uniaxial loading of stretchable gold thin-films on elastomeric substrates. Appl. Phys. Lett. 94, 071902 (2009).
Chou, H.-H. et al. A chameleon-inspired stretchable electronic skin with interactive colour changing controlled by tactile sensing. Nat. Commun. 6, 8011 (2015).
Roberts, M. E. et al. Cross-linked polymer gate dielectric films for low-voltage organic transistors. Chem. Mater. 21, 2292–2299 (2009).
Acknowledgements
X.D. acknowledges support from the Office of Naval Research through grant no. N000141812707. Y.H. acknowledges support from the National Science Foundation (EFRI-1433541).
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X.D., Y.H. and Y.-C.H. designed the experiments. Y.-C.H. performed most of the experiments including device fabrication, electrical/pressure measurements, signal processing and data analysis. Y.L. contributed to the fabrication of the flexible CMAG-WSe2 pressure sensor and related measurements. H.-C.C. contributed to the pulse wave measurements, designed the schematic illustrations and revised the first version of the manuscript. C.M. and Y.-C.H. discussed the simulation together, and C.M. executed the simulation. Q.H. contributed to the surface treatment of the microstructured moulds and gave valued feedback about the experimental results. H.W. contributed to the dielectric and electrode fabrication. C.W. provided ALD technical support. C.-Y.L. contributed to the remote pressure monitoring system. X.D., Y.H. and Y.-C.H. co-wrote the paper. All authors discussed the results and commented on the manuscript.
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Huang, YC., Liu, Y., Ma, C. et al. Sensitive pressure sensors based on conductive microstructured air-gap gates and two-dimensional semiconductor transistors. Nat Electron 3, 59–69 (2020). https://doi.org/10.1038/s41928-019-0356-5
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DOI: https://doi.org/10.1038/s41928-019-0356-5
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