Extended Data Fig. 3: Differential Scanning Calorimetry of SMRZ-1. | Nature Catalysis

Extended Data Fig. 3: Differential Scanning Calorimetry of SMRZ-1.

From: The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences

Extended Data Fig. 3

a, Differential scanning calorimetry curve for SMRZ-1 in 20 mM Tris–HCl, 20 mM KCl, 1 mM MgCl2, 0.1 mM CuSO4 buffer, pH 7.4 at total strand concentrations with 88.7 μM SMRZ-1 RNA. The calculated Tm and ΔH are indicated in the box. b, The structures of the methyl donor SAM, SAH, and the protein methyltransferase inhibitor Sinefungin SFG.

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