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Homogenous catalysis

The deuterium source matters

Deuterated compounds find applications in a variety of fields including catalysis optimization, mass spectrometry standards, pharmaceutical development and organic light emitting diodes. A recent study indicates that the choice of deuterium source significantly affects both the outcomes and mechanistic pathways in catalytic cycles.

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Fig. 1: Hydrogen/deuterium exchange efficiency with three deuterium sources.

References

  1. Atzrodt, J., Derdau, V., Reid, M. & Kerr, W. J. Angew. Chem. Int. Ed. 57, 1758–1784 (2018).

    Article  CAS  Google Scholar 

  2. Voges, R., Heys, R. & Moenius T. Preparation of Compounds Labeled with Tritium and Carbon‐14 (Wiley, 2009).

  3. Kopf, S. et al. Chem. Rev. 122, 6634–6718 (2022).

    Article  CAS  PubMed  Google Scholar 

  4. Barranco, S. et al. Nat. Catal. https://doi.org/10.1038/s41929-025-01447-x (2025).

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Correspondence to Volker Derdau.

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The author is employed at Sanofi and holds stocks and shares of the company.

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Derdau, V. The deuterium source matters. Nat Catal 8, 1264–1265 (2025). https://doi.org/10.1038/s41929-025-01460-0

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