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Organometallic complexes

The return of the nickel(I) isocyanide

Nature Catalysis volume 9, pages 234–236 (2026)Cite this article

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It is difficult to isolate and control the reactivity of nickel(I) complexes, despite their potential interest for cross-coupling reactions. Now, Mirica and colleagues report thermally robust bimetallic Ni(I) catalysts supported by isocyanide ligands that show high catalytic efficacy and selectivity in cross-coupling reactions, addressing a long-standing gap in Ni(I) chemistry.

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Fig. 1: Features, reactivities and catalysis of Ni(I)–isocyanide complexes.

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Authors and Affiliations

  1. School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen, Shenzhen, China

    Ting-Hsuan Wang & Tiow-Gan Ong

  2. Department of Applied Chemistry, National Chiayi University, Chiayi City, Taiwan

    Chen-Hsun Hung

Authors
  1. Ting-Hsuan Wang
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  2. Chen-Hsun Hung
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  3. Tiow-Gan Ong
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Corresponding authors

Correspondence to Ting-Hsuan Wang, Chen-Hsun Hung or Tiow-Gan Ong.

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Wang, TH., Hung, CH. & Ong, TG. The return of the nickel(I) isocyanide. Nat Catal 9, 234–236 (2026). https://doi.org/10.1038/s41929-026-01492-0

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