Fig. 2
From: Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin
Interaction analysis between OMD and type-I collagen. a Fibril formation assay of type-I collagen with or without OMD in a dose-dependent manner. Gradient arrow indicates the concentration of OMD (darker was higher and lighter was lower, the same hereinafter). b Direct binding assay between OMD and type-I collagen using SPR. Type-I collagen was immobilized on a CM5 sensor chip. OMD was flowed on the chip in a dose-dependent manner (0.125–2 µM). c Salt-dependent binding level of OMD for type-I collagen in SPR measurement. d Thermodynamic parameters of the interaction between OMD and type-I collagen (right) based on van’t Hoff plot (left)
