Table 1 Summary of NF1-related phenotypes seen in NF1 minipigs that underwent imaging
From: Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1
Animal ID | Generation | Sex | Age | Imaging | CALM | Freckling | Lisch nodules | Hypopigmentation | Neurofibroma | OPG | Tibial diaphysis narrowing |
|---|---|---|---|---|---|---|---|---|---|---|---|
1728 | F0 | M | 5.3 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | Absent | N/A | Bilateral |
1729 | F0 | M | 19.8 months | MRI, CT, X-ray | Present | Absent | Absent | Absent | Several in armpit region | N/A | Absent |
1730 | F0 | M | 16.7 months | MRI, CT, X-ray | Present | Absent | Present | Present | Absent | N/A | Absent |
1734 | F0 | M | 3.7 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | Absent | N/A | Bilateral |
1735 | F0 | M | 19.8 months | MRI, CT, X-ray | Present | Absent | Present | Absent | Several in armpit region | N/A | Absent |
1228 | F1 | F | 9.0 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | Absent | Present | Absent |
1229 | F1 | M | 16.1 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | Several in armpit region | Absent | Absent |
3 discrete tumors | |||||||||||
1232 | F1 | M | 15.7 months | MRI, CT, X-ray | Present | Present | N/A | Present | Several in armpit region | Absent | Absent |
5 discrete tumors | |||||||||||
1233 | F1 | M | 8.9 months | MRI, CT, X-ray | Present | Present | N/A | Absent | Absent | Absent | Absent |
1236 | F1 | F | 9.0 months | MRI, CT, X-ray | Present | Present | N/A | Present | Absent | Absent | Absent |
1342 | F1 | F | 8.8 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | Absent | Absent | Absent |
1346 | F1 | M | 9.9 months | X-ray | Present | Present | N/A | Absent | Absent | N/A | Absent |
1359 | F1 | F | 9.9 months | MRI, CT, X-ray | Present | Absent | N/A | Absent | 1 discrete tumor | Absent | Absent |
Prevalence of phenotype | 13/13 | 4/13 | 2/3 | 3/13 | 5/13 | 1/7 | 2/13 | ||||
