Fig. 5
FLIM data from diabetic and control wound edges indicate changes in the ratio of free (A1) and protein-bound (A2) NADH lifetime components. a Representative maps of A1/A2 demonstrate changes in free-to-bound NADH ratios within the epithelium defined by the dashed lines (scale bar = 100 µm). b The average A1/A2 ratio within the epithelium was lower on day 10 compared to day 3 (p < 0.0095). Boxes correspond to the first and third quartiles, and whiskers extend to the full range of the data. c The mean A1/A2 ratio obtained in vivo was also significantly correlated with the Ki67 proliferation index (p = 0.0354)
