Table 2 Twitch parameter analysis on 4-month-old mice

From: Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism

Parameters

CTL

Obsc

Obsl1

dKO

Number of analyzed muscles (females/males)

10 (6/4)

7 (3/4)

9 (4/5)

10 (4/6)

TtP (ms)

21.45 ± 1.02

26.14 ± 0.91**

21.56 ± 0.92

25.3 ± 0.74**

HRT (ms)

43.3 ± 2.81

42.86 ± 3.20

48.00 ± 5.68

46.5 ± 1.99

Full-width at half-maximum (ms)

57 ± 3.4

60 ± 3.9

63 ± 6.3

64 ± 2.6

Stress during tetanus (kPa)

71 ± 3.8

99 ± 5**

79 ± 6.2

70 ± 5.8

PCSA (mm2)

0.51 ± 0.027

0.61 ± 0.023

0.6 ± 0.034

0.55 ± 0.03

EDL muscle mass (mg)

3.4 ± 0.19

4 ± 0.22

4.3 ± 0.28**

3.9 ± 0.18

Fiber length (mm)

6.2 ± 0.11

6.1 ± 0.16

6.7 ± 0.13*

6.5 ± 0.2

  1. Values are presented as averages and standard error of mean. Samples sizes are shown in the table; p values are **p  < 0.01 or *p <   0.05 vs. CTL
  2. TtP time to peak, HRT half-relaxation time, PCSA physiological cross-sectional area, CTL control, Obsl1 obscurin-like 1, dKO double knockout, EDL extensor digitorum longus
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