Table 2 Comparison of MR1/5-OPRU tetramer staining and usage of MAIT cell-consistent CDR3α sequences within TRAV1-2+ CD8+ T cells in the bronchoalveolar (BAL) and peripheral blood (PBMC) compartments from two patients with active TB
Participant ID | Compartment | % MAIT cell-consistent CDR3α | % MR1/5-OPRU tetramer-positive | % MAIT cell-consistent CDR3α of MR1/5-OPRU tetramer-positive | % MAIT cell-consistent CDR3α of MR1/5-OPRU tetramer-negative |
|---|---|---|---|---|---|
1020 | BAL | 40.7 | 33.7 | 93.9 | 13.7 |
1020 | PBMC | 5.4 | 3.1 | 89.2 | 2.7 |
0091 | BAL | 28.5 | 5.1 | 100.0 | 24.7 |
0091 | PBMC | 18.6 | 6.3 | 71.4 | 15.1 |