Fig. 2 | Communications Biology

Fig. 2

From: Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2

Fig. 2

Recurrently mutated genes in canine osteosarcoma. a Single nucleotide variants were reported in samples subjected to both WGS and WES. Copy number variants (Log2FC < −0.9 and >0.4) and structural variants were reported in WGS samples. All mutations were clustered based on mutational burden in genes associated with chromatin/histones, TP53 and DMD. b, c Circos plots on DogID #14 and #18. Blue triangles = SNVs; red dots = amplifications; green dots = deletions; dark red arrows = intra-chromosomal translocations; dark blue arrows = inter-chromosomal translocations. WGS whole genome sequencing, WES whole exome sequencing, SNV single nucleotide variant

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