Fig. 3 | Communications Biology

Fig. 3

From: Compression-induced expression of glycolysis genes in CAFs correlates with EMT and angiogenesis gene expression in breast cancer

Fig. 3

Compression-induced expression alteration of enriched biological process-related genes. a The expression distribution analysis of the genes involved in homophilic cell adhesion, the negative and positive regulation of cell migration, and glycolysis. Based on the gene ontology from Amigo 2, the genes corresponding to each biological process were classified and analyzed. The x- and y-axis represent the average values of gene expression at different compressive stress conditions and the values of gene expression at 0.773 kPa, respectively. The genes with the values greater than or equal to 2 both in x- and y-axes were counted in the upper-right corner of graphs, whereas the genes with less than -2 value in both in x- and y-axes were counted in the lower-left corner. b The ratio presentation of the expression distribution analysis. The ratios were calculated by dividing the number of upregulated genes by that of downregulated genes. CS is the abbreviation of compressive stress. Source data are provided as Supplementary Data 1

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