Fig. 1
From: Mechanical strain promotes skin fibrosis through LRG-1 induction mediated by ELK1 and ERK signalling
LRG-1 is overexpressed in human hypertrophic scarring. a Images of normal skin, atrophic scar, and hypertrophic scar. b Images of H&E-stained sections of normal skin, atrophic scar, and hypertrophic scar. (Scale bar = 200 μm). c, d Images and quantitative analysis of immunohistochemistry staining of CD31 and LRG-1. (Scale bar = 50 μm). e, f The levels of LRG-1 mRNA and protein in different skin tissues were measured using RT-qPCR and Western blotting. Data are presented as mean ± SD. n = 20 biologically independent samples. *P < 0.05, **P < 0.01, ***P < 0.001
