Fig. 6 | Communications Biology

Fig. 6

From: Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland

Fig. 6

Re-clustered immune cell clusters C6, C8, and C9 resulted in 11 subclusters. a Feature plot highlighting C6, C8, and C9, which were putatively identified as immune cells based on high Ptprc expression in these clusters. b T-SNE plots of re-clustered immune cells. c Heatmap showing the top 5 differentially expressed genes for each of the 11 immune cell clusters. d Dendrogram highlighting the relationship among each of the immune cell sub-clusters. e Feature plots of selected genes to further classify immune cells as T cells (Cd3e, Gata3), NK cells (Klrb1c), dendritic cells (Cd24a), B cells (Cd19), macrophages (Fcgr1), and fibrocytes (Col1a1). f Feature plot of C1qa, which emerged as a differentially expressed gene between macrophage clusters I5 and I6. g Bar plots showing the distribution of cells from two independent experiments in each of the immune cell clusters. Symbols indicate individual cell distributions for each of the two experimental replicates (triangle, circle)

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