Table 3 Summary of immune clusters and expressed genes

From: Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland

ID

Vehiclea

E2a

E2+PBDEa

Key genes

Cell types

I0

30.1

14.0

12.8

Klrc1, Cd3e

NK cells/T cells

I1

29.3

2.3

2.6

Cd3e, Cd3g, Cd3d,

T cells

I2

4.6

31.2

23.5

H2-Ab1, Cd24a, Cd209a

Dendritic cells

I3

12.7

1.8

1.0

Cd3e, Gata3

T cells

I4

5.0

19.0

15.8

H2-Ab1, Cd24a, Cd19

Dendritic cells/B cells

I5

4.8

8.1

9.7

H2-Ab1, Fcgr1, Adgre1

Macrophage

I6

1.8

9.5

19.4

H2-Ab1, Fcgr1, Adgre1, C1qa, C1qb, C1qc

Macrophage (M2)

I7

5.1

3.2

0.5

Cd7e

T cells

I8

2.1

5.0

5.6

Col1a1

Fibrocytes

I9

2.0

2.7

7.1

Cd3e

T cells

I10

2.7

3.2

2.0

Col1a1

Fibrocytes

  1. aValues are presented as percentages of total number of immune cells per treatment group (e.g., 30.1% of immune cells from Vehicle treated group are clustered in I0)
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