Fig. 8 | Communications Biology

Fig. 8

From: Structural characterization of HypX responsible for CO biosynthesis in the maturation of NiFe-hydrogenase

Fig. 8

Reaction scheme of CO formation by HypX. The reaction steps 1–3 take place in the N-terminal domain to form formyl-CoA. The conformational change of formyl-CoA proceeds in the reaction step 4 from the extended to the folded conformations, by which the formyl group will be placed at the active site in the C-terminal domain to form CO. Decarbonylation of formyl-CoA takes place to form CO in the reaction step 5

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