Fig. 6: Simulated charge requirements in chronic scenario. | Communications Biology

Fig. 6: Simulated charge requirements in chronic scenario.

From: Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves

Fig. 6: Simulated charge requirements in chronic scenario.

a, b Simulated chronic charge requirements in the human computational model with 0.5 mm fibrotic tissue inside and outside of the cuff electrode. Acute and chronic comparison for pulse width 0.4 ms, 1 ms and 2 ms a, the effect of interphase delay including 0 ms, 0.1 ms (100 μs) and 0.2 ms (200 μs). c A simulated shift in human ex vivo data for 1 ms and 2 ms pulse widths based on the average of the collected ex-vivo data.

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