Table 3 Variances explained by each cSCC risk factor.

From: Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations

cSCC risk factor

Model

Hispanic/Latinos

non-Hispanic whites

  

Proportion (%) of variance explained adjusted R2

Genetic ancestry PCs

1

12.69

1.23

HIrisPlex-S skin pigmentation predictions

2

3.83

1.52

GRS based on 14 known cSCC-SNPs

3

1.01

0.43

Sun exposure (history of AK)

4

6.68

6.40

  1. PC principal components, GRS genetic risk score, AK actinic keratosis.
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